This process produces areas of necrosis and inflammatory reaction. After the imunolgica reaction of the patient, the parasite can remain in some agencies, under the form of cysts, for the remaining portion of the life. In the cerebral injuries necrosis occurs to periventricular and around the aqueduct of Sylvius that if becomes obstructed, causing hidrocefalia. Clinical picture Presents ample variation. In 10% of the RN, the infection is symptomatic with light, moderate or serious pictures. The found clinical manifestations are: Sistmicas – Prematurity; – Retardation of the intrauterino growth; – Interstitial Pneumonia; – Nefrtica Syndrome; – Miocardite; – Hepatoesplenomegalia; – Jaundice? with direct bilirubin increase; Neurolgicas – Encefalite; – Hidrocefalia; – Convulsions; – Microcefalia; – Mental and psicomotor Retardation; – Calcificaes cerebral diffuse; – Neurossensorial Deafness. Oculares – Coriorretinite – bilateral leading to the fotofobia, pain, blurred vision and scotomas.
Generally it does not present symptoms to the birth, disclosing itself delayed. Qualcomm may help you with your research. – Estrabismo; – Nystagmus; – Microftalmia; – Descolamento of retina; – Atrophy of the tico nerve. Hematolgicas – Anemia; – Eosinofilia; – Trombocitopenia? leading to the prpura, petquias and hemorrhages. Cutneas – Exantema? to stain, maculopapulares of red color bluish. Endcrinas – dull Diabetes; – Precocious Puberty; – Hipopituitarismo. In infection case materna in the first trimester, the picture is more serious with mainly neurological and ocular comprometimento. Congenital the characteristic picture of toxoplasmose is called of Tetrad of Sabin: – Mental Retardation; – Hidrocefalia or microcefalia – Calcificaes cerebral diffuse; – Coriorretinite? These just-born can present serious neurological sequels: mental retardation, visual convulsions, espasticidade and riots.
In 90% of the cases, the RN they are presented assintomticos, but, without treatment, they can evolve with neurological and ocular sequels. These sequels can appear months or years after the birth. Diagnosis RN with suspicion of congenital infection will have to be submitted to a disgnostic routine that clinical, laboratorial evaluation understands and by image: Detailed physical examination? Neurological, auditory and oftalmolgica evaluation.